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2010

FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database

8 years 1 months ago
FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
FlyTF (http://www.flytf.org) is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. The manual classification of TFs in the initial version of FlyTF that concentrated primarily on the DNA-binding characteristics of the proteins has now been extended to a more fine-grained annotation of both DNA binding and regulatory properties in the new release. Furthermore, experimental evidence from the literature was classified into a defined vocabulary, and in collaboration with FlyBase, translated into Gene Ontology (GO) annotation. While our GO annotations will also be available through FlyBase as they will be incorporated into the genes' official GO annotation in the future, the entire evidence used for classification including computational predictions and quotes from the literature can be accessed through FlyTF. The FlyTF website now builds upon the InterMine framework, which provides...
Ulrike Pfreundt, Daniel P. James, Susan Tweedie, D
Added 20 May 2011
Updated 20 May 2011
Type Journal
Year 2010
Where NAR
Authors Ulrike Pfreundt, Daniel P. James, Susan Tweedie, Derek Wilson, Sarah A. Teichmann, Boris Adryan
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