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CMSB
2006
Springer

Incorporating Time Delays into the Logical Analysis of Gene Regulatory Networks

13 years 7 months ago
Incorporating Time Delays into the Logical Analysis of Gene Regulatory Networks
Based on the logical description of gene regulatory networks developed by R. Thomas, we introduce an enhanced modelling approach that uses timed automata. It yields a refined qualitative description of the dynamics of the system incorporating information not only on ratios of kinetic constants related to synthesis and decay, but also on the time delays occurring in the operations of the system. We demonstrate the potential of our approach by analysing an illustrative gene regulatory network of bacteriophage .
Heike Siebert, Alexander Bockmayr
Added 20 Aug 2010
Updated 20 Aug 2010
Type Conference
Year 2006
Where CMSB
Authors Heike Siebert, Alexander Bockmayr
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