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BMCBI
2006

An integrated system for genetic analysis

9 years 7 months ago
An integrated system for genetic analysis
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet are easy to use. Description: We have developed an Integrated Genotyping System (IGS) to meet this need. IGS securely stores, edits and analyses genotype and phenotype data. It stores information about DNA samples, plates, primers, markers and genotypes generated by a genotyping laboratory. Data are structured so that statistical genetic analysis of both case-control and pedigree data is straightforward. Conclusion: IGS can model complex phenotypes and contain genotypes from whole genome association studies. The database makes it possible to integrate genetic analysis with data curation. The IGS web site http://bioinformatics.well.ox.ac.uk/project-igs.shtml contains further information. Background Advances in high-throughput genotyping technology mean that it is now possible to carry out very large-scale studi...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan
Added 10 Dec 2010
Updated 10 Dec 2010
Type Journal
Year 2006
Where BMCBI
Authors Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan Duan, Richard Mott
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