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BMCBI
2006
112views more  BMCBI 2006»
8 years 8 months ago
Distill: a suite of web servers for the prediction of one-, two- and three-dimensional structural features of proteins
Background: We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbo...
Davide Baù, Alberto J. M. Martin, Catherine...
BMCBI
2006
128views more  BMCBI 2006»
8 years 8 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...
BMCBI
2006
169views more  BMCBI 2006»
8 years 8 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
BMCBI
2006
94views more  BMCBI 2006»
8 years 8 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...
BMCBI
2006
129views more  BMCBI 2006»
8 years 8 months ago
Fast index based algorithms and software for matching position specific scoring matrices
Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
BMCBI
2006
223views more  BMCBI 2006»
8 years 8 months ago
PSMIX: an R package for population structure inference via maximum likelihood method
Background: Inference of population stratification and individual admixture from genetic markers is an integrative part of a study in diverse situations, such as association mappi...
Baolin Wu, Nianjun Liu, Hongyu Zhao
BMCBI
2006
117views more  BMCBI 2006»
8 years 8 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
BMCBI
2006
146views more  BMCBI 2006»
8 years 8 months ago
A database application for pre-processing, storage and comparison of mass spectra derived from patients and controls
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...
Mark K. Titulaer, Ivar Siccama, Lennard J. Dekker,...
BMCBI
2006
130views more  BMCBI 2006»
8 years 8 months ago
Laboratory Information Management Software for genotyping workflows: applications in high throughput crop genotyping
Background: With the advances in DNA sequencer-based technologies, it has become possible to automate several steps of the genotyping process leading to increased throughput. To e...
B. Jayashree, Praveen T. Reddy, Y. Leeladevi, Jona...
BMCBI
2006
126views more  BMCBI 2006»
8 years 8 months ago
A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors
Background: The development of effective frameworks that permit an accurate diagnosis of tumors, especially in their early stages, remains a grand challenge in the field of bioinf...
Andreas Keller, Nicole Ludwig, Nicole Comtesse, An...
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