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2011

Parameter estimation for Boolean models of biological networks

8 years 1 months ago
Parameter estimation for Boolean models of biological networks
Boolean networks have long been used as models of molecular networks and play an increasingly important role in systems biology. This paper describes a software package, offered as a web service, that helps users construct Boolean network models based on experimental data and biological input. The key feature is a discrete analog of parameter estimation for continuous models. With only experimental data as input, the software can be used as a tool for reverse-engineering of Boolean network models from experimental time course data. Key words: 2000 MSC: Primary 92-08, 92B05; Secondary 13P10
Elena S. Dimitrova, Luis David García-Puent
Added 15 May 2011
Updated 15 May 2011
Type Journal
Year 2011
Where TCS
Authors Elena S. Dimitrova, Luis David García-Puente, Franziska Hinkelmann, Abdul Salam Jarrah, Reinhard C. Laubenbacher, Brandilyn Stigler, Michael Stillman, Paola Vera-Licona
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