Sciweavers

481 search results - page 1 / 97
» Parameter estimation for Boolean models of biological networ...
Sort
View
TCS
2011
12 years 12 months ago
Parameter estimation for Boolean models of biological networks
Boolean networks have long been used as models of molecular networks and play an increasingly important role in systems biology. This paper describes a software package, offered ...
Elena S. Dimitrova, Luis David García-Puent...
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 6 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
AB
2008
Springer
13 years 11 months ago
Local Structure and Behavior of Boolean Bioregulatory Networks
Abstract. A well-known discrete approach to modeling biological regulatory networks is the logical framework developed by R. Thomas. The network structure is captured in an interac...
Heike Siebert
GECCO
2009
Springer
13 years 11 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
CEC
2010
IEEE
12 years 12 months ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...