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2011

Protein mass spectra data analysis for clinical biomarker discovery: a global review

8 years 1 months ago
Protein mass spectra data analysis for clinical biomarker discovery: a global review
The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. In recent years there has been a growing interest in using high throughput technologies for the detection of such biomarkers. In particular, mass spectrometry appears as an exciting tool with great potential. However, to extract any benefit from the massive potential of clinical proteomic studies, appropriate methods, improvement and validation are required. To better understand the key statistical points involved with such studies, this review presents the main data analysis steps of protein mass spectra data analysis, from the pre-processing of the data to the identification and validation of biomarkers.
Pascal Roy, Caroline Truntzer, Delphine Maucort-Bo
Added 12 May 2011
Updated 12 May 2011
Type Journal
Year 2011
Where BIB
Authors Pascal Roy, Caroline Truntzer, Delphine Maucort-Boulch, Thomas Jouve, Nicolas Molinari
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