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ISVC
2010
Springer

Visual Network Analysis of Dynamic Metabolic Pathways

11 years 8 months ago
Visual Network Analysis of Dynamic Metabolic Pathways
We extend our previous work on the exploration of static metabolic networks to evolving, and therefore dynamic, pathways. We apply our visualization software to data from a simulation of early metabolism. Thereby, we show that our technique allows us to test and argue for or against different scenarios for the evolution of metabolic pathways. This supports a profound and efficient analysis of the structure and properties of the generated metabolic networks and its underlying components, while giving the user a vivid impression of the dynamics of the system. The analysis process is inspired by Ben Shneiderman’s mantra of information visualization. For the overview, user-defined diagrams give insight into topological changes of the graph as well as changes in the attribute set associated with the participating enzymes, substances and reactions. This way, “interesting features” in time as well as in space can be recognized. A linked view implementation enables the navigation into ...
Markus Rohrschneider, Alexander Ullrich, Andreas K
Added 28 Jan 2011
Updated 28 Jan 2011
Type Journal
Year 2010
Where ISVC
Authors Markus Rohrschneider, Alexander Ullrich, Andreas Kerren, Peter F. Stadler, Gerik Scheuermann
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