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» A Bernoulli-Gaussian model for gene factor analysis
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ISMB
2004
13 years 6 months ago
Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
BMCBI
2010
216views more  BMCBI 2010»
12 years 12 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
BMCBI
2011
12 years 8 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
ICA
2007
Springer
13 years 8 months ago
Infinite Sparse Factor Analysis and Infinite Independent Components Analysis
Abstract. A nonparametric Bayesian extension of Independent Components Analysis (ICA) is proposed where observed data Y is modelled as a linear superposition, G, of a potentially i...
David Knowles, Zoubin Ghahramani
BMCBI
2004
146views more  BMCBI 2004»
13 years 4 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker