RECOMB
2015
Springer
8 years 12 days ago
2015
Springer
Young et al. [14] showed that due to gene length bias the popular Fisher Exact Test should not be used to study the association between a group of differentially expressed (DE) ge...
RECOMB
2015
Springer
8 years 12 days ago
2015
Springer
Clustered regularly interspaced short palindromic repeats (CRISPR) are structured regions in bacterial and archaeal genomes, which are part of an adaptive immune system against pha...
RECOMB
2015
Springer
8 years 12 days ago
2015
Springer
Many microbes associate with higher eukaryotes and impact their vitality. In order to engineer microbiomes for host benefit, we must understand the rules of community assembly and...
RECOMB
2015
Springer
8 years 12 days ago
2015
Springer
A fundamental problem in the study of phylogenetic networks is how to determine whether a phylogenetic network displays a phylogenetic tree or not. We develop a quadratic-time alg...
RECOMB
2015
Springer
8 years 12 days ago
2015
Springer
Identifying phase information is biomedically important due to the association of complex haplotype effects, such as compound heterozygosity, with disease. As recent next-generat...
RECOMB
2012
Springer
11 years 7 months ago
2012
Springer
Background: Paralog reduction, the loss of duplicate genes after whole genome duplication (WGD) is a pervasive process. Whether this loss proceeds gene by gene or through deletion...
RECOMB
2012
Springer
11 years 7 months ago
2012
Springer
Abstract. Since the first emergence of protein-protein interaction networks, more than a decade ago, they have been viewed as static scaffolds of the signaling-regulatory events ...
RECOMB
2012
Springer
11 years 7 months ago
2012
Springer
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
RECOMB
2012
Springer
11 years 7 months ago
2012
Springer
Abstract. Lateral gene transfer (LGT) is a common mechanism of nonvertical evolution where genetic material is transferred between two more or less distantly related organisms. It ...
RECOMB
2012
Springer
11 years 7 months ago
2012
Springer
Signaling networks are essential for cells to control processes such as growth and response to stimuli. Although many “omic” data sources are available to probe signaling pathw...