Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
- Gene regulatory networks allow us to study and understand genes’ roles in biological processes. Among others, regulatory networks help to identify pathway initiator genes and t...
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...