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» A Discriminative Framework for Detecting Remote Protein Homo...
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RECOMB
2002
Springer
14 years 6 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
JCB
2002
116views more  JCB 2002»
13 years 5 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
13 years 6 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
HAIS
2009
Springer
13 years 10 months ago
Incremental Kernel Machines for Protein Remote Homology Detection
Abstract. Protein membership prediction is a fundamental task to retrieve information for unknown or unidentified sequences. When support vector machines (SVMs) are associated with...
Lionel Morgado, Carlos Pereira