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» A Markov Chain Approach to Reconstruction of Long Haplotypes
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ALMOB
2007
151views more  ALMOB 2007»
13 years 6 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
BMCBI
2005
122views more  BMCBI 2005»
13 years 5 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...
BIRD
2007
Springer
150views Bioinformatics» more  BIRD 2007»
14 years 5 days ago
Bayesian Inference for 2D Gel Electrophoresis Image Analysis
Two-dimensional gel electrophoresis (2DGE) is a technique to separate individual proteins in biological samples. The 2DGE technique results in gel images where proteins appear as d...
Ji Won Yoon, Simon J. Godsill, ChulHun Kang, Tae-S...
BMCBI
2008
132views more  BMCBI 2008»
13 years 6 months ago
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes thr
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...