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» A New Constraint Solver for 3D Lattices and Its Application ...
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LPAR
2005
Springer
13 years 10 months ago
A New Constraint Solver for 3D Lattices and Its Application to the Protein Folding Problem
Abstract. The paper describes the formalization and implementation of an efficient constraint programming framework operating on 3D crystal lattices. The framework is motivated an...
Alessandro Dal Palù, Agostino Dovier, Enric...
LATIN
2004
Springer
13 years 10 months ago
Combinatorial Problems on Strings with Applications to Protein Folding
We consider the problem of protein folding in the HP model on the 3D square lattice. This problem is combinatorially equivalent to folding a string of 0’s and 1’s so that the s...
Alantha Newman, Matthias Ruhl
BMCBI
2010
116views more  BMCBI 2010»
13 years 4 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
RECOMB
2002
Springer
14 years 5 months ago
Revealing protein structures: a new method for mapping antibody epitopes
A recent idea for determining the three-dimensional structure of a protein uses antibody recognition of surface structure and random peptide libraries to map antibody epitope comb...
Brendan Mumey, Brian W. Bailey, Edward A. Dratz