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CBMS
2008
IEEE
13 years 11 months ago
A New Path Length Measure Based on GO for Gene Similarity with Evaluation using SGD Pathways
We propose a new method for measuring the semantic similarity of genes based on path length between their annotation terms in the Gene Ontology. Our method applies an exponential ...
Anurag Nagar, Hisham Al-Mubaid
IJBRA
2008
88views more  IJBRA 2008»
13 years 4 months ago
GOSAP: Gene Ontology-Based Semantic Alignment of Biological Pathways
A large number of biological pathways have been assembled in later years, and are being stored in databases. Hence, the need for methods to analyse these pathways has emerged. One ...
Jonas Gamalielsson, Björn Olsson
BICOB
2011
Springer
12 years 4 months ago
Similarity and Prioritization of Disease Proteins using Path Length Measure
Semantic similarity measures have been used successfully and extensively in the biomedical research with various applications. As the biomedical ontologies, which form the main gro...
Anurag Nagar, Hisham Al-Mubaid
BMCBI
2006
169views more  BMCBI 2006»
13 years 4 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
BMCBI
2008
173views more  BMCBI 2008»
13 years 4 months ago
Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
Stephen W. Tanner, Pankaj Agarwal