18 search results - page 2 / 4 » A Novel Approach to Remote Homology Detection: Jumping Align... |
BIOINFORMATICS
2005
13 years 5 months ago
2005
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
BMCBI
2005
13 years 5 months ago
2005
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
ALMOB
2008
13 years 5 months ago
2008
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
JCB
2007
13 years 5 months ago
2007
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
WABI
2009
Springer
13 years 11 months ago
2009
Springer
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...