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BMCBI
2010
117views more  BMCBI 2010»
13 years 5 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
BMCBI
2010
140views more  BMCBI 2010»
13 years 2 months ago
An improved machine learning protocol for the identification of correct Sequest search results
Background: Mass spectrometry has become a standard method by which the proteomic profile of cell or tissue samples is characterized. To fully take advantage of tandem mass spectr...
Morten Kallberg, Hui Lu
PKDD
2009
Springer
118views Data Mining» more  PKDD 2009»
13 years 11 months ago
Protein Identification from Tandem Mass Spectra with Probabilistic Language Modeling
This paper presents an interdisciplinary investigation of statistical information retrieval (IR) techniques for protein identification from tandem mass spectra, a challenging probl...
Yiming Yang, Abhay Harpale, Subramaniam Ganapathy
BMCBI
2011
13 years 6 days ago
MRCQuant- an accurate LC/MS relative isotopic quantification algorithm on TOF instruments
Background: Relative isotope abundance quantification, which can be used for peptide identification and differential peptide quantification, plays an important role in liquid chro...
William H. Haskins, Konstantinos Petritis, Jianqiu...
BMCBI
2007
157views more  BMCBI 2007»
13 years 5 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...