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RE
2008
Springer
13 years 4 months ago
Design Science, Engineering Science and Requirements Engineering
For several decades there has been a debate in the computing sciences about the relative roles of design and empirical research, and about the contribution of design and research ...
Roel Wieringa, J. M. G. Heerkens
BMCBI
2010
277views more  BMCBI 2010»
13 years 5 months ago
PCA2GO: a new multivariate statistics based method to identify highly expressed GO-Terms
Background: Several tools have been developed to explore and search Gene Ontology (GO) databases allowing efficient GO enrichment analysis and GO tree visualization. Nevertheless,...
Marc Bruckskotten, Mario Looso, Franz Cemic, Anne ...
BMCBI
2005
141views more  BMCBI 2005»
13 years 5 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
BMCBI
2006
202views more  BMCBI 2006»
13 years 5 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...