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» A Study in Empirical and 'Casuistic' Analysis of Ontology Ma...
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BMCBI
2008
145views more  BMCBI 2008»
13 years 5 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
CIBCB
2007
IEEE
13 years 9 months ago
Associative Artificial Neural Network for Discovery of Highly Correlated Gene Groups Based on Gene Ontology and Gene Expression
Abstract-- The advance of high-throughput experimental technologies poses continuous challenges to computational data analysis in functional and comparative genomics studies. Gene ...
Ji He, Xinbin Dai, Xuechun Zhao
SEMWEB
2010
Springer
13 years 3 months ago
How to Reuse a Faceted Classification and Put It on the Semantic Web
There are ontology domain concepts that can be represented according to multiple alternative classification criteria. Current ontology modeling guidelines do not explicitly conside...
Bene Rodriguez-Castro, Hugh Glaser, Leslie Carr
BMCBI
2011
13 years 24 days ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
BMCBI
2010
95views more  BMCBI 2010»
13 years 5 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling