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» A Survey of Computational Methods for Determining Haplotypes
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RECOMB
2002
Springer
14 years 6 months ago
A Survey of Computational Methods for Determining Haplotypes
It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (...
Bjarni V. Halldórsson, Vineet Bafna, Nathan...
RECOMB
2003
Springer
14 years 6 months ago
Haplotype reconstruction from SNP alignment
In this paper, we describe a method for statistical reconstruction of haplotypes from a set of aligned SNP fragments. We consider the case of a pair of homologous human chromosome...
Lei Li, Jong Hyun Kim, Michael S. Waterman
JCB
2006
140views more  JCB 2006»
13 years 5 months ago
HAPLOFREQ-Estimating Haplotype Frequencies Efficiently
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
Eran Halperin, Elad Hazan
RECOMB
2003
Springer
14 years 6 months ago
Large scale reconstruction of haplotypes from genotype data
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Eleazar Eskin, Eran Halperin, Richard M. Karp
BMCBI
2007
165views more  BMCBI 2007»
13 years 5 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...