It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (...
In this paper, we describe a method for statistical reconstruction of haplotypes from a set of aligned SNP fragments. We consider the case of a pair of homologous human chromosome...
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...