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» A Transcriptional Approach to Gene Clustering
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BMCBI
2006
134views more  BMCBI 2006»
13 years 5 months ago
An approach for clustering gene expression data with error information
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
Brian Tjaden
RECOMB
2007
Springer
14 years 5 months ago
Learning Gene Regulatory Networks via Globally Regularized Risk Minimization
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
Yuhong Guo, Dale Schuurmans
JCB
2006
83views more  JCB 2006»
13 years 5 months ago
A Discrete-Event Approach to Transcription Control with Dynamic Event-Controllability
This paper presents a discrete-event approach to synthesis of transcription control for a class of (computational) gene networks. Given a set of genes and protein-gene and/or prote...
Peter C. Y. Chen
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 5 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
IMSCCS
2006
IEEE
13 years 11 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng