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GECCO
2009
Springer
146views Optimization» more  GECCO 2009»
13 years 9 months ago
Evolving specific network statistical properties using a gene regulatory network model
Abstract. The generation of network topologies with specific, userspecified statistical properties is the aim of this paper. This is achieved through the use of an artifical Gene R...
Miguel Nicolau, Marc Schoenauer
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 6 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
EMO
2005
Springer
108views Optimization» more  EMO 2005»
13 years 10 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
BIOCOMP
2008
13 years 6 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
CEC
2010
IEEE
13 years 6 days ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...