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CIBCB
2005
IEEE
13 years 11 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...
BMCBI
2007
197views more  BMCBI 2007»
13 years 5 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
GECCO
2004
Springer
132views Optimization» more  GECCO 2004»
13 years 11 months ago
Optimizing Topology and Parameters of Gene Regulatory Network Models from Time-Series Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. Different approaches to infer the dependencies of gene r...
Christian Spieth, Felix Streichert, Nora Speer, An...
CEC
2005
IEEE
13 years 11 months ago
Clustering-based approach to identify solutions for the inference of regulatory networks
Abstract- In this paper we address the problem of finding valid solutions for the problem of inferring gene regulatory networks. Different approaches to directly infer the depende...
Christian Spieth, Felix Streichert, Nora Speer, An...
BMCBI
2006
126views more  BMCBI 2006»
13 years 5 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron