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» A custom FPGA for the simulation of gene regulatory networks
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BMCBI
2006
127views more  BMCBI 2006»
13 years 5 months ago
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
Bor-Sen Chen, Yu-Chao Wang
IJCAI
2001
13 years 7 months ago
Qualitative Simulation of Genetic Regulatory Networks: Method and Application
Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simu...
Hidde de Jong, Michel Page, Céline Hernande...
BMCBI
2010
143views more  BMCBI 2010»
13 years 5 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
AB
2008
Springer
14 years 4 days ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte
CMSB
2006
Springer
13 years 9 months ago
Regulatory Network Reconstruction Using Stochastic Logical Networks
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
Bartek Wilczynski, Jerzy Tiuryn