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» A graphical model for predicting protein molecular function
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JCC
2008
92views more  JCC 2008»
13 years 5 months ago
Fast procedure for reconstruction of full-atom protein models from reduced representations
: We introduce PULCHRA, a fast and robust method for the reconstruction of full-atom protein models starting from a reduced protein representation. The algorithm is particularly su...
Piotr Rotkiewicz, Jeffrey Skolnick
WOB
2008
101views Bioinformatics» more  WOB 2008»
13 years 6 months ago
Top-Down Hierarchical Ensembles of Classifiers for Predicting G-Protein-Coupled-Receptor Functions
Abstract. Despite the recent advances in Molecular Biology, the function of a large amount of proteins is still unknown. An approach that can be used in the prediction of a protein...
Eduardo P. Costa, Ana Carolina Lorena, André...
BMCBI
2005
116views more  BMCBI 2005»
13 years 5 months ago
SuperLigands - a database of ligand structures derived from the Protein Data Bank
Background: Currently, the PDB contains approximately 29,000 protein structures comprising over 70,000 experimentally determined three-dimensional structures of over 5,000 differe...
Elke Michalsky, Mathias Dunkel, Andrean Goede, Rob...
ICML
2004
IEEE
14 years 6 months ago
A graphical model for protein secondary structure prediction
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...
Wei Chu, Zoubin Ghahramani, David L. Wild
BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
13 years 10 months ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...