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BMCBI
2010
136views more  BMCBI 2010»
13 years 4 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
RECOMB
2005
Springer
14 years 5 months ago
Comparison of Protein-Protein Interaction Confidence Assignment Schemes
Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing protein interaction networks for various species at a...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
BMCBI
2008
124views more  BMCBI 2008»
13 years 4 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo
BMCBI
2007
227views more  BMCBI 2007»
13 years 4 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
BMCBI
2008
170views more  BMCBI 2008»
13 years 4 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou