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» A hybrid genetic search for multiple sequence alignment
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IPPS
2003
IEEE
13 years 10 months ago
Using Hybrid Alignment for Iterative Sequence Database Searches
Progressive sequence model refinement by means of iterative searches is an effective technique for high sensitivity database searches and is currently employed in popular tools s...
Yuheng Li, Mario Lauria, Ralf Bundschuh
GECCO
2003
Springer
129views Optimization» more  GECCO 2003»
13 years 10 months ago
Evolutionary Two-Dimensional DNA Sequence Alignment
This article presents a model for DNA sequence alignment. In our model, a finite state automaton writes two-dimensional maps of nucleotide sequences. An evolutionary method for se...
Edgar E. Vallejo, Fernando Ramos
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
ICNSC
2008
IEEE
13 years 11 months ago
Multiple Sequence Alignment Based on Genetic Algorithms with Reserve Selection
— This paper presents an approach to the multiple sequence alignment (MSA) problem by applying genetic algorithms with a reserve selection mechanism. MSA is one of the most funda...
Yang Chen, Jinglu Hu, Kotaro Hirasawa, Songnian Yu
BMCBI
2005
142views more  BMCBI 2005»
13 years 4 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds