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BMCBI
2006
169views more  BMCBI 2006»
13 years 5 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
BMCBI
2010
106views more  BMCBI 2010»
13 years 5 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
ISCAS
2006
IEEE
108views Hardware» more  ISCAS 2006»
13 years 11 months ago
Design methodology for global resonant H-tree clock distribution networks
Abstract—Design guidelines for resonant H-tree clock distribution networks are presented in this paper. A distributed model of a two-level resonant H-tree structure is described,...
Jonathan Rosenfeld, Eby G. Friedman
BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
CANDC
2004
ACM
13 years 5 months ago
The iProClass integrated database for protein functional analysis
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...