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BMCBI
2004
158views more  BMCBI 2004»
13 years 5 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
13 years 11 months ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster
GECCO
2003
Springer
128views Optimization» more  GECCO 2003»
13 years 10 months ago
Evolving Consensus Sequence for Multiple Sequence Alignment with a Genetic Algorithm
In this paper we present an approach that evolves the consensus sequence [25] for multiple sequence alignment (MSA) with genetic algorithm (GA). We have developed an encoding schem...
Conrad Shyu, James A. Foster
BMCBI
2008
176views more  BMCBI 2008»
13 years 5 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
COCOA
2007
Springer
13 years 11 months ago
A New Dynamic Programming Algorithm for Multiple Sequence Alignment
Abstract. Multiple sequence alignment (MSA) is one of the most basic and central tasks for many studies in modern biology. In this paper, we present a new progressive alignment alg...
Jean-Michel Richer, Vincent Derrien, Jin-Kao Hao