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BMCBI
2007
153views more  BMCBI 2007»
13 years 4 months ago
A new pairwise kernel for biological network inference with support vector machines
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
RECOMB
2002
Springer
14 years 5 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
ICANN
2001
Springer
13 years 9 months ago
Learning and Prediction of the Nonlinear Dynamics of Biological Neurons with Support Vector Machines
Based on biological data we examine the ability of Support Vector Machines (SVMs) with gaussian kernels to learn and predict the nonlinear dynamics of single biological neurons. We...
Thomas Frontzek, Thomas Navin Lal, Rolf Eckmiller
RECOMB
2004
Springer
14 years 5 months ago
A class of edit kernels for SVMs to predict translation initiation sites in eukaryotic mRNAs
The prediction of translation initiation sites (TISs) in eukaryotic mRNAs has been a challenging problem in computational molecular biology. In this paper, we present a new algori...
Haifeng Li, Tao Jiang
ISNN
2005
Springer
13 years 10 months ago
Scaling the Kernel Function to Improve Performance of the Support Vector Machine
Abstract. The present study investigates a geometrical method for optimizing the kernel function of a support vector machine. The method is an improvement of the one proposed in [4...
Peter Williams, Sheng Li, Jianfeng Feng, Si Wu