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» A pattern for almost compositional functions
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BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
13 years 3 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen
BMCBI
2007
102views more  BMCBI 2007»
13 years 5 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
BMCBI
2007
107views more  BMCBI 2007»
13 years 5 months ago
antiCODE: a natural sense-antisense transcripts database
Background: Natural antisense transcripts (NATs) are endogenous RNA molecules that exhibit partial or complete complementarity to other RNAs, and that may contribute to the regula...
Yifei Yin, Yi Zhao, Jie Wang, Changning Liu, Shugu...
APLAS
2006
ACM
13 years 11 months ago
Scheme with Classes, Mixins, and Traits
Abstract. The Scheme language report advocates language design as the composition of a small set of orthogonal constructs, instead of a large accumulation of features. In this pape...
Matthew Flatt, Robert Bruce Findler, Matthias Fell...
BMCBI
2010
109views more  BMCBI 2010»
13 years 5 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...