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» A quantitative approach to functional debugging
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BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2007
126views more  BMCBI 2007»
13 years 5 months ago
Including probe-level uncertainty in model-based gene expression clustering
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
Xuejun Liu, Kevin K. Lin, Bogi Andersen, Magnus Ra...
AMC
2006
67views more  AMC 2006»
13 years 5 months ago
A general probabilistic model of the PCR process
Earlier work by Saha et al. rigorously derived a general probabilistic model for the PCR process that includes as a special case the Velikanov-Kapral model where all nucleotide re...
Nilanjan Saha, Layne T. Watson, Karen Kafadar, Ale...
BMCBI
2006
99views more  BMCBI 2006»
13 years 5 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
146views more  BMCBI 2006»
13 years 5 months ago
Optimized Particle Swarm Optimization (OPSO) and its application to artificial neural network training
Background: Particle Swarm Optimization (PSO) is an established method for parameter optimization. It represents a population-based adaptive optimization technique that is influen...
Michael Meissner, Michael Schmuker, Gisbert Schnei...