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CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
13 years 11 months ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
BMCBI
2010
97views more  BMCBI 2010»
13 years 3 months ago
Preprocessing of gene expression data by optimally robust estimators
Background: The preprocessing of gene expression data obtained from several platforms routinely includes the aggregation of multiple raw signal intensities to one expression value...
Matthias Kohl, Hans-Peter Deigner
BMCBI
2010
193views more  BMCBI 2010»
13 years 5 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
BMCBI
2004
131views more  BMCBI 2004»
13 years 5 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
BMCBI
2007
120views more  BMCBI 2007»
13 years 5 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...