28 search results - page 2 / 6 » A rule-based framework for gene regulation pathways discover... |
BMCBI
2010
13 years 5 months ago
2010
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
RECOMB
2010
Springer
13 years 7 months ago
2010
Springer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
BMCBI
2006
13 years 5 months ago
2006
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
BMCBI
2007
13 years 5 months ago
2007
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
RECOMB
2006
Springer
14 years 5 months ago
2006
Springer
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...