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» A search algorithm for fixed-composition protein design
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JCC
2006
57views more  JCC 2006»
13 years 4 months ago
A search algorithm for fixed-composition protein design
: We present a computational protein design algorithm for finding low-energy sequences of fixed amino acid composition. The search algorithms used in protein design typically do no...
Geoffrey K. Hom, Stephen L. Mayo
JCC
2008
166views more  JCC 2008»
13 years 4 months ago
Reference energy extremal optimization: A stochastic search algorithm applied to computational protein design
: We adapt a combinatorial optimization algorithm, extremal optimization (EO), for the search problem in computational protein design. This algorithm takes advantage of the knowled...
Naigong Zhang, Chen Zeng
BIOCOMP
2006
13 years 6 months ago
A Multi-strategy Approach to Protein Structural Alphabet Design
- The search for structural similarity among proteins can provide valuable insights into their functional mechanisms and their functional relationships. Though the protein 1D seque...
Shih-Yen Ku, Yuh-Jyh Hu
BMCBI
2008
87views more  BMCBI 2008»
13 years 4 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
IPPS
2007
IEEE
13 years 11 months ago
A Comparative Study of Parallel Metaheuristics for Protein Structure Prediction on the Computational Grid
A comparative study of parallel metaheuristics executed in grid environments is proposed, having as case study a genetic algorithm, a simulated annealing algorithm and a random se...
Alexandru-Adrian Tantar, Nouredine Melab, El-Ghaza...