Comparison of 3-dimensional protein folds is a core problem in molecular biology. The Contact Map Overlap (CMO) scheme provides one of the most common measures for protein structur...
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...