20 search results - page 1 / 4 » A stepwise framework for the normalization of array CGH data |
BMCBI
2005
13 years 4 months ago
2005
Background: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly...
BMCBI
2006
13 years 4 months ago
2006
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
BMCBI
2010
13 years 4 months ago
2010
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
BMCBI
2008
13 years 4 months ago
2008
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
BMCBI
2005
13 years 4 months ago
2005
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...