Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
We investigate incremental word learning with few training examples in a Hidden Markov Model (HMM) framework suitable for an interactive learning scenario with little prior knowle...
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
- Aligning specific sequences against other known sequences in a database is a central aspect of bioinformatics. New experimental data being added continuously to these databases n...