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GCB
2006
Springer
136views Biometrics» more  GCB 2006»
13 years 8 months ago
Ab Initio Prediction of Molecular Fragments from Tandem Mass Spectrometry Data
: Mass spectrometry is one of the key enabling measurement technologies for systems biology, due to its ability to quantify molecules in small concentrations. Tandem mass spectrome...
Markus Heinonen, Ari Rantanen, Taneli Mielikä...
ECCB
2008
IEEE
13 years 6 months ago
Towards de novo identification of metabolites by analyzing tandem mass spectra
Abstract. Mass spectrometry is among the most widely used technologies in proteomics and metabolomics. For metabolites, de novo interpretation of spectra is even more important tha...
Sebastian Böcker, Florian Rasche
BMCBI
2010
152views more  BMCBI 2010»
13 years 4 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
BMCBI
2008
184views more  BMCBI 2008»
13 years 4 months ago
"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI
Background: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecule...
Pornpat Nikamanon, Elroy Pun, Wayne Chou, Marek D....
BMCBI
2011
12 years 8 months ago
PI: An open-source software package for validation of the SEQUEST result and visualization of mass spectrum
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...
Yantao Qiao, Hong Zhang, Dongbo Bu, Shiwei Sun