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» Accurate Prediction of Orthologous Gene Groups in Microbes
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NAR
2006
120views more  NAR 2006»
13 years 6 months ago
TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
Blaise T. F. Alako, Daphne Rainey, Harm Nijveen, J...
BMCBI
2010
101views more  BMCBI 2010»
13 years 6 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
BMCBI
2006
128views more  BMCBI 2006»
13 years 6 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
13 years 11 months ago
Reconstructing Phylogenetic Networks Using Maximum Parsimony
Phylogenies—the evolutionary histories of groups of organisms—are one of the most widely used tools throughout the life sciences, as well as objects of research within systema...
Luay Nakhleh, Guohua Jin, Fengmei Zhao, John M. Me...