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NAR
2008
152views more  NAR 2008»
13 years 5 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
BMCBI
2006
112views more  BMCBI 2006»
13 years 5 months ago
Distill: a suite of web servers for the prediction of one-, two- and three-dimensional structural features of proteins
Background: We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbo...
Davide Baù, Alberto J. M. Martin, Catherine...
BMCBI
2011
13 years 14 days ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
BMCBI
2011
12 years 9 months ago
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....
BMCBI
2008
134views more  BMCBI 2008»
13 years 5 months ago
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...