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2008

PROMALS3D web server for accurate multiple protein sequence and structure alignments

8 years 9 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and phylogenetic analysis. We report PROMALS3D web server for constructing alignments for multiple protein sequences and/or structures using information from available 3D structures, database homologs and predicted secondary structures. PROMALS3D shows higher alignment accuracy than a number of other advanced methods. Input of PROMALS3D web server can be FASTA format protein sequences, PDB format protein structures and/or user-defined alignment constraints. The output page provides alignments with several formats, including a colored alignment augmented with useful information about sequence grouping, predicted secondary structures and consensus sequences. Intermediate results of sequence and structural database searches are also available. The PROMALS3D web server is available at: http://prodata.swmed.edu/ proma...
Jimin Pei, Ming Tang, Nick V. Grishin
Added 14 Dec 2010
Updated 14 Dec 2010
Type Journal
Year 2008
Where NAR
Authors Jimin Pei, Ming Tang, Nick V. Grishin
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