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GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 6 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
TSE
2011
134views more  TSE 2011»
13 years 22 days ago
Verifying the Evolution of Probability Distributions Governed by a DTMC
— We propose a new probabilistic temporal logic iLTL which captures properties of systems whose state can be represented by probability mass functions (pmf’s). Using iLTL, we c...
YoungMin Kwon, Gul A. Agha
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
13 years 11 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
POPL
2008
ACM
14 years 6 months ago
Systems biology, models, and concurrency
Models will play a central role in the representation, storage, manipulation, and communication of knowledge in systems biology. Models capable of fulfilling such a role will like...
Walter Fontana
BMCBI
2010
104views more  BMCBI 2010»
13 years 5 months ago
Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...
Anil Sorathiya, Andrea Bracciali, Pietro Liò...