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RECOMB
2010
Springer
13 years 6 months ago
An Algorithmic Framework for Predicting Side-Effects of Drugs
Abstract. One of the critical stages in drug development is the identification of potential side effects for promising drug leads. Large scale clinical experiments aimed at discove...
Nir Atias, Roded Sharan
BMCBI
2008
118views more  BMCBI 2008»
13 years 4 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
BMCBI
2007
129views more  BMCBI 2007»
13 years 4 months ago
HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Hongya Zhao, Hong Yan
WWW
2007
ACM
14 years 5 months ago
Organizing and searching the world wide web of facts -- step two: harnessing the wisdom of the crowds
As part of a large effort to acquire large repositories of facts from unstructured text on the Web, a seed-based framework for textual information extraction allows for weakly sup...
Marius Pasca
BMCBI
2006
111views more  BMCBI 2006»
13 years 4 months ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover