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BIOINFORMATICS
2004
99views more  BIOINFORMATICS 2004»
13 years 5 months ago
EST clustering error evaluation and correction
Motivation: The gene expression intensity information conveyed by (EST) Expressed Sequence Tag data can be used to infer important cDNA library properties, such as gene number and...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, James Leeb...
BMCBI
2011
13 years 10 days ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
WOB
2007
116views Bioinformatics» more  WOB 2007»
13 years 6 months ago
Validating Gene Clusterings by Selecting Informative Gene Ontology Terms with Mutual Information
Abstract. We propose a method for global validation of gene clusterings. The method selects a set of informative and non-redundant GO terms through an exploration of the Gene Ontol...
Ivan G. Costa, Marcílio Carlos Pereira de S...
ICASSP
2011
IEEE
12 years 9 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero
CSB
2004
IEEE
136views Bioinformatics» more  CSB 2004»
13 years 9 months ago
Minimum Entropy Clustering and Applications to Gene Expression Analysis
Clustering is a common methodology for analyzing the gene expression data. In this paper, we present a new clustering algorithm from an information-theoretic point of view. First,...
Haifeng Li, Keshu Zhang, Tao Jiang