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BMCBI
2007
165views more  BMCBI 2007»
13 years 5 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Islands of Tractability for Parsimony Haplotyping
We study the parsimony approach to haplotype inference, which calls for finding a set of haplotypes of minimum cardinality that explains an input set of genotypes. We prove that ...
Roded Sharan, Bjarni V. Halldórsson, Sorin ...
HIS
2008
13 years 6 months ago
Towards a Highly Scalable Hybrid Metaheuristic for Haplotype Inference Under Parsimony
Haplotype Inference is a challenging problem in bioinformatics that consists in inferring the basic genetic constitution of diploid organisms on the basis of their genotype. This ...
Stefano Benedettini, Luca Di Gaspero, Andrea Roli
CPM
2009
Springer
122views Combinatorics» more  CPM 2009»
13 years 11 months ago
Haplotype Inference Constrained by Plausible Haplotype Data
The haplotype inference problem (HIP) asks to find a set of haplotypes which resolve a given set of genotypes. This problem is of enormous importance in many practical fields, su...
Michael R. Fellows, Tzvika Hartman, Danny Hermelin...