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BMCBI
2006
119views more  BMCBI 2006»
13 years 5 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2007
148views more  BMCBI 2007»
13 years 5 months ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...
BMCBI
2007
121views more  BMCBI 2007»
13 years 5 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
GPEM
2000
80views more  GPEM 2000»
13 years 5 months ago
Explanatory Analysis of the Metabolome Using Genetic Programming of Simple, Interpretable Rules
Genetic programming, in conjunction with advanced analytical instruments, is a novel tool for the investigation of complex biological systems at the whole-tissue level. In this stu...
Helen E. Johnson, Richard J. Gilbert, Michael K. W...
BMCBI
2004
150views more  BMCBI 2004»
13 years 5 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk