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» An integrated Bayesian analysis of LOH and copy number data
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BMCBI
2010
170views more  BMCBI 2010»
13 years 5 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
ICASSP
2007
IEEE
13 years 11 months ago
Wavelet Footprints and Sparse Bayesian Learning for DNA Copy Number Change Analysis
Alterations in the number of DNA copies are very common in tumor cells and may have a very important role in cancer development and progression. New array platforms provide means ...
Roger Pique-Regi, En-Shuo Tsau, Antonio Ortega, Ro...
BMCBI
2010
101views more  BMCBI 2010»
13 years 5 months ago
Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
Zhengdong D. Zhang, Mark B. Gerstein
BMCBI
2010
134views more  BMCBI 2010»
13 years 5 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BMCBI
2007
113views more  BMCBI 2007»
13 years 4 months ago
Statistical tools for transgene copy number estimation based on real-time PCR
Background: As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughpu...
Joshua S. Yuan, Jason N. Burris, Nathan R. Stewart...