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BMCBI
2008
124views more  BMCBI 2008»
13 years 5 months ago
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
Romesh Stanislaus, Mark Carey, Helena F. Deus, Kev...
BMCBI
2007
176views more  BMCBI 2007»
13 years 5 months ago
Genome Expression Pathway Analysis Tool - Analysis and visualization of microarray gene expression data under genomic, proteomic
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
Markus Weniger, Julia C. Engelmann, Jörg Schu...
BICOB
2010
Springer
13 years 6 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
BMCBI
2007
166views more  BMCBI 2007»
13 years 5 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
BMCBI
2005
112views more  BMCBI 2005»
13 years 5 months ago
Visualization methods for statistical analysis of microarray clusters
Background: The most common method of identifying groups of functionally related genes in microarray data is to apply a clustering algorithm. However, it is impossible to determin...
Matthew A. Hibbs, Nathaniel C. Dirksen, Kai Li, Ol...