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CSB
2004
IEEE
158views Bioinformatics» more  CSB 2004»
13 years 9 months ago
Algorithms for Association Study Design Using a Generalized Model of Haplotype Conservation
There is considerable interest in computational methods to assist in the use of genetic polymorphism data for locating disease-related genes. Haplotypes, contiguous sets of correl...
Russell Schwartz
BMCBI
2010
134views more  BMCBI 2010»
13 years 5 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BMCBI
2010
84views more  BMCBI 2010»
13 years 5 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2008
195views more  BMCBI 2008»
13 years 5 months ago
Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
Fredrik Pettersson, Andrew P. Morris, Michael R. B...
BMCBI
2008
109views more  BMCBI 2008»
13 years 5 months ago
Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis
Background: Correctly merged data sets that have been independently genotyped can increase statistical power in linkage and association studies. However, alleles from microsatelli...
Angela P. Presson, Eric M. Sobel, Paivi Pajukanta,...